Actionable genomic risk that fits a routine visit.
ARC-OMIX is built around your workflow. Once the tests launch, ordering will take minutes, and results will arrive with an interpretation guide written for clinicians and patient-facing materials for the visit. The ARC-PREVENT panel for proactive profiling and ARC-CHOL, for when a specific indication is in front of you, are both coming soon.
The ARC-PREVENT panel is coming soon.
Borderline risk category
LDL of 140 and a Pooled Cohort Equations estimate of 6.5%, just below the 7.5% statin-discussion threshold. A top-decile CHD polygenic score from ARC-PREVENT reclassifies the patient and supports earlier statin consideration.
Family history
Father had an MI at 52; no severe hypercholesterolemia variant found; standard workup clean. The ARC-PREVENT CHD polygenic score further quantifies the heritable load so you can decide whether earlier screening or treatment is warranted.
Proactive risk profiling
A motivated 45-year-old with no symptoms. The ARC-PREVENT panel returns percentile and absolute risk across five conditions, letting you personalize screening intervals and counseling.
Track your order through the ARC-OMIX portal.
Sign in to the ARC-OMIX portal, select the panel or test, and confirm. It takes a few minutes.
Saliva collection materials ship directly to the patient with a prepaid return label; or provide a requisition for a blood draw at any phlebotomy lab. No visit required.
Report delivered to the ordering provider via the secure portal after specimen receipt, with decision support written for clinicians.
The report includes a plain-language summary to hand to the patient and talking-point guidance for each risk tier.
Structured around how clinicians decide.
Each report answers the two questions clinicians ask: how high is this patient’s risk, and what should I do about it?
Request sample reportIllustrative pedigree, not a real family. The arrow marks your patient. Cascade testing is included at low cost with ARC-CHOL for first-degree relatives of a confirmed pathogenic-variant carrier.
One confirmed variant opens testing for the whole family.
When ARC-CHOL finds a pathogenic variant, the result matters beyond your patient: one confirmed variant prompts testing across first-degree relatives — parents, siblings, and children.
ABGC-certified genetic counselors are available by telehealth, and counseling is triggered automatically on monogenic-positive findings.
Clinician FAQs
For billing and order-logistics questions, see the Orders FAQ on Pricing.
How is ARC-OMIX different from other PRS testing services?
ARC-OMIX combines clinical context with integrated genomic risk that includes validated, ancestry-calibrated PRS, rare-variant classification, and family history in one report.
Does insurance cover the test?
ARC-OMIX is not in-network with any payer; testing will be self-pay at launch. We provide a superbill on request, which patients may be able to submit for HSA/FSA reimbursement.
How does PRS perform across ancestries?
PRS performance varies by genetic ancestry, a legacy of Euro-centric GWAS training data. ARC-OMIX addresses this with ensemble scoring and genotype-derived ancestry calibration.
What conditions are covered?
The ARC-PREVENT prevention panel covers five conditions — coronary heart disease, chronic kidney disease, abdominal aortic aneurysm, atrial fibrillation, and type 2 diabetes — in two tiers (Essential and Premium). ARC-CHOL, our indication-based test for severe hypercholesterolemia, launches alongside it; additional indication-based tests are in development.
What happens if a sample fails?
We re-run the test at no charge. If a second sample is needed, we ship new collection materials at our expense.
How is patient data protected?
Patient data and reports are stored in a HIPAA-compliant, encrypted environment.
How do I get added to the ordering portal?
Sign up with your NPI, state of license, and practice details.
Get ready for launch.
ARC-PREVENT and ARC-CHOL launch together. Review the evidence now, and create a free clinician portal account with your NPI so you can order the day they launch.